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所在位置:所有产品 > 抗体抗原 > 一抗 > HFE2抗体
HFE2抗体图片
产品货号:
Z37545
中文名称:
HFE2抗体
英文名称:
Anti-HFE2 Antibody (Clone#1D7)
产品规格:
100μg(vial)
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-HFE2 Antibody (Clone#1D7)
指标别名Hemochromatosis type 2 protein;Hemojuvelin;HFE2;HFE2A;HJV;JH;RGM domain family member C;RGMC
克隆性Monoclonal
检验物种human
应用范围IP,FCM
基因名称HFE2
克隆号1D7
抗体来源Mouse
免疫原Recombinant human RGMC (aa 36-398).
计算分子量45kDa
成分Each vial contains 0.02% sodium azide.
纯化方式Protein G-affinity purified.
浓度0.5~1mg/mL,actual concentration vary by lot.Use suggested dilution ratio to decide dilution procedure.
产品形态溶液
背景资料Hemojuvelin (HJV/RGMc/HFE2) is a membrane-bound and soluble protein in mammals.It is a member of the repulsive guidance molecule family of proteins.The product of this gene is involved in iron metabolism.It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression.It could also represent the cellular receptor for hepcidin.Two uORFs in the 5' UTR negatively regulate the expression and activity of the encoded protein.Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.Defects in this gene are the cause of hemochromatosis type 2A,also called juvenile hemochromatosis (JH).JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism,hepatic fibrosis or cirrhosis and cardiomyopathy,occurring typically before age of 30.
Uniprot IDQ6ZVN8
基因名全称Hemojuvelin
蛋白名全称Hemojuvelin (HFE2)
推荐稀释比User need to optimize the dilution ratio for this antibody

相关搜索:HFE2抗体HFE2单抗Anti-HFE2 Antibody (Clone#1D7)
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